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cGMP can also be seen to mediate the switching on in the attraction of apical dendrites of pyramidal cells in cortical layer V toward semaphorin-3A (Sema3a).[5] While the axons of pyramidal cells are repelled by Sema3a, the apical dendrites are drawn to it. The attraction is mediated by the enhanced levels of soluble guanylate cyclase (SGC) which a